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NBC News reported that experts say these supplements are "most likely ineffective for weight loss" and often contain "older weight loss supplements that are rebranded." The ingredients frequently include compounds like ashwagandha and green tea extract that have been recycled from previous generations of diet products

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The composition of the HFD was 77% fat and sucrose, 14% protein, and 9% carbohydrates (Table 1) 34

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Body weight, though not directly factored into dosing algorithms, influences pharmacokinetics