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However, it should be mentioned that, for technical reasons, siRNA-based knockdown of CYPOR was never complete
What the clinical data shows From the Phase 2 trial: Two patterns stand out
Hu M, Shu X, Wu X, et al
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Secondary endpoints were defined as pharmacodynamics and pharmacokinetic parameters including maximum serum concentration, time to maximum concentration, half-life, plasma clearance, and volume of distribution, as well as exploratory parameters including bodyweight, glycemic control, and overall hormone profile
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