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Through the FGF21SIRT1 axis, FGF21 may shift from a protective to a dysregulatory role, exacerbating hepatic lipid accumulation and metabolic imbalance in advanced disease stages
Liraglutide causes large and rapid epicardial fat reduction
Semaglutide still the GLP-1 heavyweight If Novo Nordisks semaglutide were counted as a single drug, it would be second bestselling drug of 2023, with total sales of $19.93 billion compared to Keytrudas (pembrolizumab) $25.01 billion
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