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That distinction targeted fat pathway versus systemic GH-axis stimulation is the core of why researchers choose one over the other, and it shapes everything from their evidence base to their regulatory status

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Glutathione, the principal antioxidant and detoxifying agent produced by the liver, helps neutralise toxins, pollutants, and metabolic wastes, allowing them to be eliminated from the body more easily

Primary bile acids (cholic acid and chenodeoxycholic acid) synthesized by the liver are conjugated with glycine or taurine before secretion into bile, stored in the gallbladder, and released into the intestine postprandially to facilitate absorption of lipid-soluble nutrients