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10.1101/683359 bioRxiv [Preprint] 60 Dello RussoC.CappoliN.ColettaI.MezzogoriD.PacielloF.PozzoliG.et al (2018)
Pro-inflammatory M1 macrophages accumulating in thyroid tissue secrete hepcidin and ferritin, altering iron homeostasis and increasing oxidative stress, which in turn promotes thyroid follicular cell ferroptosis (182)
After the 6-wk chronic ethanol feeding, the most striking difference between WT and KO mice was the complete prevention of steatosis development in KO mice
Eloralintide's top dose arm produced the higher reported number: 20.1% mean weight reduction at 9 mg over 48 weeks, versus 11.8% for cagrilintide 2.4 mg over 68 weeks
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