While the mechanism is still being studied, here are a few of the proposed reasons why semaglutide can cause diarrhea: It slows gut motility: Semaglutide slows gastric emptying and motility throughout the GI tract
5-year follow-up of the randomised diabetes remission clinical trial (DiRECT) of continued support for weight loss maintenance in the UK: an extension study
Ozempic (semaglutide for type 2 diabetes) Ozempic contains the same drug as Wegovy (semaglutide) but is licensed for type 2 diabetes and has a lower maximum dose of 2 mg
Suryadevara V, Roy A, Sahoo J, Kamalanathan S, Naik D, Mohan P, et al
The science is promising enough to study closely, but practical decisions should wait for stronger evidence, regulatory decisions, and individualized medical guidance