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It has been reported that sorafenib can induce ferroptosis in tumor cells through the p62-kelch-like ECH-associated protein 1-NRF2 pathway to achieve anti-tumor efficacy (33)
The HepG2 cell line was purchased from ATCC (HB-8065)
In vitro and in vivo toxicity assessment of the senotherapeutic Peptide 14 Type of study: non-rct in vitro Number of citations: 6 Year: 2022 Authors: Alessandra Zonari, L
The twist is that a subset of gut bacteria can chew on L-carnitine and related nutrients and make a small volatile compound called trimethylamine or TMA
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Reduced levels in the body can lead to heart disease, cancer, obesity, and reduced cognitive function
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