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The compound has been shown to restore decorin expression, which may help explain why GHK-Cu-treated skin often looks smoother even when collagen content changes are modest
[11] Long-term metformin therapy reduces calcium-dependent intrinsic-factor binding, lowering B12 absorption and potentially necessitating higher or more frequent parenteral doses
PubMed 15
Promotion of Angiogenesis (Blood Vessel Formation) Another core element of tissue repair is the formation of new blood vessels, known as angiogenesis
Human trials are needed
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