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Indeed, early in vitro studies on rat thyroid follicular cells showed that concurrent treatment with insulin and TSH significantly increased the cell number compared to treatment with TSH alone (Tramontano et al., 1986)

If obesity worsens after treatment discontinuation, retreatment is generally permitted only after the patient has undergone at least 6 months of an off-treatment period of structured lifestyle interventions equivalent to those required at treatment initiation

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Timothy Garvey 1