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Chronically elevated insulin, visceral fat, systemic inflammation, and oxidative stress are deeply intertwined with the hallmarks of aging (like cellular senescence and mitochondrial dysfunction)

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[6] [7] [8] [9] [10] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [21] [22] Estrogens are contraindicated in patients with an active or past history of thrombophlebitis, thromboembolism, thromboembolic disease, stroke, or myocardial infarction (MI)

Half of GLP-1 users told KFF the drugs are difficult to afford, and the brand-name versions have run past $1,000 a month at list price