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Description

They are not approved for this use and their effects on performance need further study

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The DIO1 gene is located on chromosome 1p32.3 and is composed of 5 exons that generate five alternatively spliced mRNAs, each of which encodes a distinct protein isoform

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While most patients initially achieve remission, approximately 30-80% of patients experience CD19-positive relapse 1 , highlighting the need to improve therapeutic efficacy

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