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191 MohapatraARJeevaratnamK
JAMA 2016;315:2424-34
Measure Lipid Metabolism Obesity is characterized by an imbalance between lipogenesis (the process of synthesizing and storing fat) and lipolysis (the breakdown of stored lipids for energy)
Valemetostat, a dual EZH1/EZH2 inhibitor approved for relapsed/refractory adult T-cell leukemia/lymphoma (ATL), acts by removing H3K27me3-mediated chromatin condensation to restore tumor suppressor gene expression
Presented for research literature review only Perkovic V et al
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