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ECC5004 further strengthens our existing pipeline addressing both incretin and non-incretin pathways, including our GLP-1/glucagon dual agonist [AZD9550] and long-acting amylin analogue [AZD6234]." Under the terms of the agreement, Eccogene will receive an initial upfront payment of $185 million

Clinical trials of semaglutide showed that gastrointestinal symptoms, including constipation, occurred in 26% of participants receiving the highest maintenance doses