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In the US, GLP-1 spending rose from $13 to $72 billion in just five years, making approval tough for patients without diabeteseven as data for arthritis risk and cardiovascular benefits grow

However, the effectiveness of TrumpRx.gov has been criticized by health experts, who say the site does not actually offer discounts for people who have insurance and may be able to pay even lower out-of-pocket prices

Persistent ulceration beyond three weeks requires urgent referral per NICE guidance to exclude serious pathology

It contains semaglutide, a GLP-1 receptor agonist that was FDA-approved for chronic weight management in 2021