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These cohorts were similar in terms of demographic and key clinical factors, despite disparities in the available sample sizes, providing confidence that the separation of these analyses did not impose selection bias on our study

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SELECT trial: GLP-1 RAs in non-diabetic patients The SELECT trial represented a paradigm shift by evaluating semaglutide exclusively in patients without diabetes

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As nocebo behavior can lead in several consequences, such as polypharmacy and worse disease outcomes, physicians need to recognize patients with risk factors for nocebo behavior and cautiously communicate biosimilars efficacy and safety, in order to prevent nocebo phenomena [179]

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