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Trials in HIV patients showed 15 to 20 percent reductions in visceral fat over 26 weeks, with modest overall weight change

Key secondary endpoints include minimal disease activity and the composite of ACR50 + PASI100 (complete skin clearance) at Week 16, which means they're measuring both joint and skin outcomes simultaneously

Semaglutide is a prescription medication approved by the FDA to help manage type 2 diabetes (Ozempic) and to support long-term weight loss (Wegovy)

to separate the serum, which was subsequently stored at -80C until further analysis

Semaglutide and B6 are appropriate for adults who have not seen success with conventional weight loss strategies and have a body mass index (BMI) of 30 or above, or 27 or above accompanied by at least one weight-related health issue, such as high blood pressure or type 2 diabetes