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Corcoran RB, Atreya CE, Falchook GS, Kwak EL, Ryan DP, Bendell JC, Hamid O, Messersmith WA, Daud A, Kurzrock R, Pierobon M, Sun P, Cunningham E, Little S, Orford K, Motwani M, Bai Y, Patel K, Venook AP, Kopetz S
In addition, fasting-induced improvements in insulin sensitivity and reductions in systemic inflammation may indirectly support gonadal steroidogenesis by restoring optimal Leydig cell responsiveness, which is crucial for testosterone production [58]
This effect was achieved through the activation of the SIRT3-related metabolic pathway
PubMed+1 Mozaffarian, D., et al
Dysregulation of ferroptosis-related genes in granulosa cells associates with impaired oocyte quality in polycystic ovary syndrome
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