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They treated 8 pouchees with the GLP-1 drug Liraglutide (trade name Saxenda ) in a well-designed, placebo-controlled, double-blind, cross-over clinical trial and showed a 35% reduction in toilet frequency on treatment compared to placebo, a reduction in urgency and better stool consistency and the drug was safe and well tolerated

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Increase by 100250 mcg increments every 12 weeks depending on tolerance

This process removes water under vacuum at low temperatures, making the peptide stable for shipping and storage