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The decision requires individualized assessment of disease activity, stability of remission, and the presence of comorbid conditions such as diabetes or obesity that might benefit from semaglutide therapy
While glucagon-like peptide-1 (GLP-1)-based medications are primarily used to treat type 2 diabetes and obesityand are known for their positive effects on body weight and blood sugar regulationpotential side effects and impacts on the gastrointestinal tract are also important
M., & Al-Madani, W
The mechanistic case is compelling
the endpoints are weight, HbA1c, and other surrogates over trial-length follow-up
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