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Shuai Wei, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The k red value of 1.4 10 6 M 1 s 1 for PfGrx C88S (SH) 2 is about two orders of magnitude higher than the highest k ox value for PfGrx C32S/C88S (SSG) in accordance with a physiological relevance of glutaredoxins as deglutathionylating enzymes

Muscle Oxygen Supply L-carnitine may also help with muscle tissue oxygenation (5)

Precursor Supplements (e.g., NAC or Glycine): These help the body produce more of its own glutathione