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Together with the similar catalytic efficiency of VviOMT3 alleles from low-methoxypyrazine varieties, this suggests that varietal differences in methoxypyrazine levels is not due to altered enzyme function but instead due to variations in gene expression

Some patients report softer stools or mild nausea, which usually resolve within 1-2 weeks as the body acclimates

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Xiang, J., Ding, X