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They reduce appetite, slow gastric emptying, increase feelings of fullness and at pharmacological doses produce significant reductions in caloric intake that result in substantial weight loss
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Moreover, in addition to the direct action of GIP in adipose tissue to reduce serum triglyceride levels, GLP-1 may abolish the postprandial rise in triglyceride and free fatty acid concentrations by reducing intestinal absorption of dietary lipid, stemmed from the delayed gastric emptying (197, 198)
Clinical Evidence on Weight Loss Maintenance with Continued Treatment Long-term semaglutide therapy demonstrates sustained weight loss when treatment continues without interruption
This is the most concrete discrepancy found
