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Cytokines and inflammatory markers, including tumor necrosis factor-alpha (TNF-) and interleukins 1 or 6 (IL-1, IL-6), further indicate the level of hepatocyte-macrophage apoptosis (Hu et al., 2025)

Considering clinical utility, subtle decline in aging tissues but not in the blood in normal subjects suggests that a decline in systemic blood circulation reflects a chronic disease setting

its pH-responsive disassembly mechanism outperforms non-pH-responsive strategies [69]

Complex regional pain syndrome patient immunoglobulin M has pronociceptive effects in the skin and spinal cord of tibia fracture mice

Indeed, ROS can oxidize methionine residues (methionine sulfoxides) within proteins and potentially impair their activities