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Se delivery to neurons by SELENOP is accomplished via its receptor, low-density lipoprotein receptor-related protein 8 (LRP8, also known as ApoER2, Figure 1) (Burk et al., 2007)

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doi:10.1016/j.tips.2013.01.001

Future research should focus on optimizing GPS formulations and conducting rigorous RCTs, standardizing botanical drug characterization, translating preclinical findings into effective therapies

BPC-157 has been associated with modulation of dopaminergic and serotonergic signaling pathways, both of which are essential for emotional balance, motivation, and cognitive processing