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GSTs were shown to catalyze the conjugation between various xenobiotics with electrophilic centers (Figure 1) and the nucleophilic GSH, thus tagging the xenobiotic for vacuolar sequestration (Martinoia et al., 1993)
doi:10.1071/rd14165
Park EY, Shimura N, Konishi T, et al
Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity
It can be difficult to sort out hyperammonemia-induced seizure versus seizure-induced hyperammonemia
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