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CY, DH and WS conceived and designed the review

Lipotropic injections, conversely, are unlicensed combinations of amino acids and vitamins marketed for weight loss, lacking robust clinical evidence and NHS endorsement

The mechanism is real: GHK-Cu activates Wnt/beta-catenin signaling, reduces androgen receptor sensitivity, and suppresses the perifollicular inflammation that quietly chokes follicles over time

The review stresses that while promising, large RCTs are missing

After microneedling, product choice matters, since acids, fragrance, and harsh exfoliants can sting through fresh channels and trigger inflammation that lasts longer than needed