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In older adults, lifestyle modifications remain a significant challenge [11, 20], and the increasing burden of NCDs further underscores the strategic role of pharmacotherapy as part of a comprehensive strategy of the obesity management
Its mechanism of action involves appetite suppression, and its efficacy can be sustained through modifications in diet and lifestyle
Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma
According to a two-hit developmental model of accelerated aging (Belsky and Shalev, 2016
GLP-1 agonists excel at weight reduction and cardiovascular protection, while SGLT2 inhibitors lead in renal preservation and heart failure management
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