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Escalation: After the initial four weeks, the dose is increased to 5 mg once weekly
Although retatrutide's mechanism of action is designed to minimise the risk of hypoglycaemia when used as monotherapy, certain groups of patients may face a higher risk, particularly as the drug is being studied in populations already managing type 2 diabetes or obesity with existing medications
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This means intrinsic factor, as well as other factors required for B 12 absorption, are not available
10.1016/j.mad.2019.01.004 Mech
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