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Safety was assessed in all participants exposed to at least one dose of the trial product

There are concerns about the development of diabetes and metabolic syndrome with long-term use

The host and gut microbes exist in a symbiotic relationship, in which the host creates a nutrient-rich environment for microbes, and the microbes, in turn, impact host physiology, immunology, and metabolism 239

For the WT virus, only one line was observed at CL, even at high concentrations (10 6 PFU/mL)

GLP-1 receptor agonists share a class-level concern during pregnancy because these receptors influence fetal pancreatic development and metabolic signaling