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Older adults may need slower dose escalation to minimize side effects
[2] Pharmacokinetic studies demonstrate rapid systemic distribution with peak plasma levels occurring within 30-60 minutes of intramuscular injection, followed by extensive hepatic storage and enterohepatic recycling
Aagaard, N
A thinner needle (higher gauge) causes less discomfort but draws medication more slowly, which is why many patients use a wider drawing needle and switch to a thinner needle before injecting
These injections last just under a week, so it is recommended to receive the injections twice a week, and include a Vitamin B12 shot for maximum benefit
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