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Gastrointestinal symptoms (more common with oral preparations): Mild nausea or upset stomach Diarrhoea (typically with very high doses) Other effects: Headache, particularly when treatment is first initiated Dizziness or light-headedness Skin reactions such as mild rash or itching Temporary reddish discolouration of urine (chromaturia) after hydroxocobalamin injections, which is harmless It is important to note that many symptoms attributed to B12 supplementation may actually represent the body's response to correcting a deficiency
see Fig
furosemide) can increase urinary excretion of thiamine and thereby lower B levels over time
By bypassing the digestive system, injections deliver nutrients directly into the bloodstream resulting in higher bioavailability and faster onset
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