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It works by binding to the ghrelin receptor (GHS-R1a) in the hypothalamus and pituitary, triggering a calcium/PKC signaling cascade that releases stored growth hormone, while separately blunting somatostatin's inhibitory signal
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A., Talebi, A., Swinnen, J
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Eating large or heavy meals may cause discomfort and make it harder for semaglutide to work effectively
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