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Consistent with our findings in mice, liraglutide treatment caused a 1.6 logfold increase in PCSK1 expression in the -1 subcluster compared with control (Figure 4, A and B, and Supplemental Figure 4A
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[48] A 2024 systematic review of 6 studies found that while lean body mass was unchanged in some cases, there were instances of significant decreases in lean body mass (040%)
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