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Considering the folate content, foods containing all components of the cereal grain (the whole grain concept) are more suitable for nutrition than those containing highly refined cereal products 304,305,306,334

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Higher IGF1 levels might be associated with higher risk of a cancer diagnosis because of subtle influences on renewal dynamics of epithelial-cell populations: somatic cells of individuals with higher levels of IGF1 might show slightly higher proliferation rates and have a slightly increased chance of survival in the presence of genetic damage, because of the anti-apoptotic effects of IGF1