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The only human trial with BPC-157 involved the intra-articular (inside the joint) administration of the peptide in 16 patients with knee osteoarthritis
Specifically, nerve damage caused by vitamin B12 most often affects the extremities (hands and feet)
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Rare but serious risks include pancreatitis, gallbladder disease, acute kidney injury (secondary to dehydration from GI effects), and a theoretical thyroid C-cell tumor risk based on rodent data that has not been confirmed in human post-marketing surveillance
It may help repair damage caused by ulcers, inflammatory bowel disease (IBD), and leaky gut syndrome, promoting a healthier digestive tract
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