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The pharmacokinetics of methotrexate and its 7-hydroxy metabolite in patients with rheumatoid arthritis

Mitochondrial Dysfunction Neuronal ATP formation depends on mitochondrial aerobic respiration, which normally produces hydrogen peroxide and superoxide radicals as byproducts during mitochondrial oxidative phosphorylation (9)

The role of oxidative stress in the pathogenesis of age-related macular degeneration

Mean difference (MD) and 95% confidence interval (CI) were used for pooling continuous data

Researchers suggest that methylation defects and impaired DNA repair caused by disturbed folate metabolism contribute to carcinogenesis