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Amer Assoc Cancer Res 21, 1980

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Having nutritional support to minimize the loss of lean body mass and bone mass, and to ensure adequate dietary intake of nutrients, is essential while taking a GLP-1 medication

Evidence type: Human RCT | Observational | Animal | In vitro | Regulatory Mechanism of Action As a copper chelator, GHK-Cu modulates over 4,000 human genes, upregulating those involved in tissue remodeling (e.g., collagen I, III) and downregulating pro-inflammatory pathways like NF-B

390 PLA 2 also converts PIP2 to DAG and IP3, like PLC, to activate PKC, 450 regulating superoxide production and cytoskeletal rearrangement