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At 5 mg (50 units at 10 mg/mL): The first therapeutic dose

Imaging demonstrates various manifestations, including diffuse abnormalities in the supratentorial white matter, reduced brain volume, diffuse cerebral edema, basal ganglia calcifications, and delayed myelination [78, 79]

1 There may even be a correlation between severity of autism and the degree of vitamin B 12 deficiency

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