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And that's been tested by
Chen W, Gullett JM, Tweedell RE, Kanneganti TD
Indeed, whereas nutlin-3 pretreatment suppressed erastin2-induced cell death in U-2 OS cells expressing an empty control vector, this condition enhanced ferroptosis in U-2 OS cells overexpressing MRP1 (Fig S2B)
For biological assays, stock solutions prepared in DMSO can be diluted into sterile laboratory buffers or culture media immediately prior to application
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Understanding these mechanisms reveals why peptides targeting various pathways may provide benefits that single-target medications cannot match
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