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Neurogenesis and neurotrophic factors Adult hippocampal neurogenesis is the process in which new neurons are generated in the hippocampus, a brain region critical for cognitive functioning, anxiety and depression-related behavior [156, 157]
In addition, ES has been shown to modulate microglia directly after the stress paradigm [182], as well as lastingly into adulthood [9, 23], possibly exerting effects on key developmental processes like synaptic pruning [183]
Notably, strong cryo-EM densities were observed in the crevices between TM1 and TM2 of the three complexes (Fig
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