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The convenience and consistency of self-administering in the abdomen outweigh any potential advantages of more difficult local injections
Nature 544 , 185190 (2017)
Interestingly, GLP-1RAs have been reported to activate the metabolism of brown fat and increase the energy expenditure in rodents through exercise activities independent of the sympathetic nervous system pathway (3)
Some patients have found benefit in combining their GLP-1 therapy with supportive peptides
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