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& Schlame, M
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This is not a reason to start metformin on its own, but it is a relevant consideration if metformin is already part of the clinical conversation
In TRIUMPH-1, the first large Phase 3 trial (a large human trial with thousands of participants) in adults with obesity, retatrutide produced an average weight loss of 28.3% at the 12 mg dose after 80 weeks
Since it promotes protein synthesis and inhibits proteolysis (muscle breakdown), its often used as a bridge between cycles or during cutting phases
They are an excellent plant protein, fiber, potassium, folate, zinc, and iron source
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