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Hydroxocobalamin, the form most commonly used in the UK, may cause: Injection site reactions (pain, redness, or swelling) Temporary reddish discolouration of urine Rarely, hypersensitivity reactions Very rarely, hypokalaemia in severely deficient patients when treatment is initiated (potassium levels should be monitored in severe deficiency) B12 injections are considered very safe, with no upper tolerable limit established, as excess B12 is excreted in urine

These precautions are not unique to BPC-157 but apply to any injectable peptide compounded outside of a pharmaceutical manufacturing environment

Zaffanello, M., et al

Both of these agents deserve respect, and the safety data is there to support their use under proper medical guidance

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