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If you have a normal amount, adding more doesnt add benefits, but it does pose the risk of side effects, he says
In animal studies, DSIP demonstrated anxiolytic effects, reducing anxiety-like behavior in mice (Shekunova et al., 2002), and lowering plasma corticosterone levels in rats (Kovalzon et al., 1997)
A synthetic peptide thats been in the news lately is semaglutide, aka GLP-1s (like Ozempic or Wegovy)
Similarly, Insulin-like growth factor 1 hair cell protection from neomycin damage is lost by inhibition of Akt or MEK signaling, suggesting that growth factor otoprotection may operate on a similar set of downstream targets (Hayashi et al., 2003
doi: 10.3389/fimmu.2014.00461 15
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