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The dual GIP/GLP-1 mechanism of tirzepatide means it cannot be directly substituted with semaglutide doses
This medicine is mainly used to treat Vitamin B12 deficiency in people with anaemia and peripheral neuropathy (nerve pain in hands and feet)
TRIUMPH-4: knee osteoarthritis plus obesity, the trial reported in December 2025
Those experiencing injection site reactions may benefit from rotating injection sites
Vitamin B12 shots are cyanocobalamin injections, a man-made form of vitamin B12
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