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A genome-wide methylation analysis revealed that high IMF levels were highly correlated with the hypermethylation of the promoters of three genes: ATP binding cassette subfamily A member 1 ( ABCA1 ), COL6A1 , and glutathione S-transferase theta 1-like ( GSTT1L )

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Some clinical trials have investigated glutathiones effects on skin pigmentation, and there is limited evidence that high-dose glutathione supplementation may reduce melanin production over time

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B.HyotylainenT.NielsenT.JensenB

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