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The same analysis flagged a higher adverse-event relative risk for retatrutide (RR 4.10 vs 2.78), consistent with a higher gastrointestinal burden at the top doses
This often coincides with the body initial adaptive response to rapid weight loss
doi: 10.1016/j.mehy.2004.04.009 43 MorrisGAndersonGMaesM
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However, individual responses vary, and some patients tolerate one GLP-1 medication without allodynia while experiencing it on another
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