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We have included substrate activation (the Hill term on the right) and found that if we omitted this substrate activation then the cytochrome oxidase reactions did not produce enough NAPQI at high overdoses
J Appl Physiol 1993;75(6):241924
In addition, loss of glutathione peroxidase 4 (GPX4), a central regulator of ferroptosis, leads to hemolytic anemia and increases spleen erythroid progenitor death through receptor-interacting protein 3 (RIP3)-dependent necroptosis signaling 48
Noh Y, Yin H, Yu OHY, Bitton A, Azoulay L
Milani A, Basirnejad M, Shahbazi S, Bolhassani A
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