Human relevance would require sufficient published, peer-reviewed controlled human studies, appropriate regulatory review, pharmacokinetic characterization, toxicology data, and long-term safety evaluation
The 0.9% benzyl alcohol content inhibits bacterial growth, allowing multi-use of the vial
An important note on folate: if B12 deficiency is suspected, folate deficiency should not be corrected in isolation before B12 status has been assessed and treated, as doing so can precipitate or worsen neurological complications
People who cannot absorb vitamin B 12 should continue to eat a well-balanced diet that provides other nutrients (folic acid, iron, and vitamin C) necessary to produce healthy blood cells
Very low or high blood levels of homocysteine can indicate a B12, folate, and/or B6 deficiency (21)