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doi:10.1172/jci.insight.123614 64
- Overview Takeda Pharmaceutical Ltd
An acute glucose-lowering effect of DPP-4 inhibition in a rodent model of T2DM (the obese Zucker rat) was demonstrated when it was shown that a different inhibitor (isoleucine thiazolidide) reduced plasma DPP-4 activity and was associated with a larger insulin response and improved glucose tolerance after an oral glucose load (when endogenous GLP-1 secretion would be stimulated) (26)
Non-synthetic peptides include insulin (for blood sugar regulation), collagen peptides (for skin and joint health), and glutathione (for detoxification and immune support)
However, other clinical studies suggest these medications may actually protect against certain types of stones, such as uric acid stones, by changing urine chemistry
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